• Users Online: 712
  • Print this page
  • Email this page
Year : 2018  |  Volume : 1  |  Issue : 2  |  Page : 35-42

Molecular mechanisms involved in angiogenesis and potential target of antiangiogenesis in human glioblastomas

Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, China

Correspondence Address:
Dr. Bao-Hui Liu
Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/glioma.glioma_10_17

Rights and Permissions

Glioblastoma multiforme (GBM) is the most devastating and common primary malignant brain tumor in adults. Angiogenesis as a hallmark in glioblastoma has attracted more and more attention of the research community. Over the past years, several systematic studies have provided vital results in this field discovering alterations in unanticipated number of genes and other regulatory factors and the associated signaling pathways. Recent discoveries about such genes and signaling pathway associated with angiogenesis in GBM provide a picture of the genomic routes in angiogenesis and antiangiogenesis pathways and may lay the foundation for improved antiangiogenesis therapy and clinical care. In this review, we discuss several such recent progresses in the genes associated with GBM angiogenesis/antiangiogenesis pathways and explore the potential new targets for GBM treatment.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded705    
    Comments [Add]    
    Cited by others 10    

Recommend this journal