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Year : 2020  |  Volume : 3  |  Issue : 4  |  Page : 162-167

Re-understanding of edema zone from the nerve fiber bundles: A narrative review

Department of Radiation and Medical Oncology, Zhongnan Hospital, Wuhan University, Wuhan, Hubei Province, China

Correspondence Address:
Dr. Yahua Zhong
Department of Zhongnan Hospital, Wuhan University, Shuiguohu Street, 168 Donghu Road, Wuhan
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/glioma.glioma_28_20

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Spread along nerve fiber bundles is one of the most important modes of glioma invasion; however, the current guidelines for radiotherapy target areas recommend a 1–2-cm margin in all directions from the tumor border based on pretreatment imaging findings. In this article, we analyzed the relationship between edema and nerve fiber bundles in 60 glioma patients and aimed to clarify the effect of including edema on delineation of the target volume.

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