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Postoperative radiotherapy with concomitant temozolomide plus anlotinib for newly diagnosed glioblastoma: Study protocol for a multicenter, double-blind, randomized phase II trial
Yuanyuan Chen1, Baiqiang Dong1, Guihong Liu2, Pengfei Sun3, Meihua Li4, Xuejun Yang5, Shiyu Feng6, Liang Wang7, Yonghong Hua8, Ming Zhao9, Yanhui Liu10, Juntao Ran11, Li Qiao12, Xueguan Lu13, Hao Jiang14, Deqiang Mao15, Junxin Wu16, Xianming Li17, Wei Zheng18, Zhigang Liu19, Song Lin20, Meiling Deng1, Qunying Yang21, Chengcheng Guo21, Jing Li22, Zhong-ping Chen21
1 Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University, Guangzhou, Guangdong Province, China
2 Department of Radiation Oncology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu Province, China
3 Department of Radiation Oncology, Lanzhou University Second Hospital, Lanzhou, Gansu Province, China
4 Department of Neurosurgery, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi Province, China
5 Department of Neurosurgery, Internet Hospital of Tianjin Medical University General Hospital, Tianjin, China
6 Department of Neurosurgery, Chinese PLA General Hospital, Beijing, China
7 Department of Neurosurgery, Tangdu Hospital, Xi'an, Shaanxi Province, China
8 Department of Radiation Oncology, The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, Zhejiang Province, China
9 Department of Neurosurgery, Henan Cancer Hospital, Zhengzhou, Henan Province, China
10 Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China
11 Department of Radiation Oncology, The First Hospital of Lanzhou University, Lanzhou, Gansu Province, China
12 Department of Neurosurgery, Gansu Provincial Hospital, Lanzhou, Gansu Province, China
13 Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, China
14 Department of Radiation Oncology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui Province, China
15 Department of Neurosurgery, Chongqing University Cancer Hospital, Chongqing, China
16 Department of Radiation Oncology, Fujian Cancer Hospital, Fuzhou, Fujian Province, China
17 Department of Radiation Oncology, Shenzhen People's Hospital, Shenzhen, Guangdong Province, China
18 Department of Neurosurgery, The Sixth Medical Center of PLA General Hospital, Beijing, China
19 Department of Radiation Oncology, The Fifth Affiliated Hospital Sun Yat-sen University, Zhuhai, Guangdong Province, China
20 Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
21 Department of Neurosurgery/Neuro-oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University, Guangzhou, Guangdong Province, China
22 Department of Radiology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University, Guangzhou, Guangdong Province, China
Correspondence Address:
Dr. Zhong-ping Chen
Department of Neurosurgery/Neuro-Oncology, Sun Yat-sen University Cancer Center, 651 East Dongfeng Road, Guangzhou 510060
China
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/glioma.glioma_17_22
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