Glioma

REVIEW
Year
: 2022  |  Volume : 5  |  Issue : 2  |  Page : 50--55

The role of collagens in glioma: A narrative review


Yi Wang, Toshiya Ichinose, Mitsutoshi Nakada 
 Department of Neurosurgery, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan

Correspondence Address:
Dr. Mitsutoshi Nakada
Department of Neurosurgery, Graduate School of Medical Science, Kanazawa University
Japan

Glioma is the most common brain tumor in the central nervous system and characterized by diffuse invasion into adjacent brain tissue. The extracellular matrix (ECM) is an essential component of the tumor microenvironment and it contributes to tumor progression through close interactions with glioma cells. Accumulated evidence has indicated that collagen levels, which are the most critical components of the ECM, are elevated in gliomas and collagen contributes to glioma progression. In this review, we provide a comprehensive summary of the roles of various collagens in glioma. A better understanding of the interactions of various collagens with glioma cells may provide new therapeutic strategies for gliomas.


How to cite this article:
Wang Y, Ichinose T, Nakada M. The role of collagens in glioma: A narrative review.Glioma 2022;5:50-55


How to cite this URL:
Wang Y, Ichinose T, Nakada M. The role of collagens in glioma: A narrative review. Glioma [serial online] 2022 [cited 2022 Oct 2 ];5:50-55
Available from: http://www.jglioma.com/article.asp?issn=2589-6113;year=2022;volume=5;issue=2;spage=50;epage=55;aulast=Wang;type=0