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  Indian J Med Microbiol
 

Figure 2: Immunohistochemical staining for delta-like ligand 4, Ki67, and CD34 expression. (A and B) Positive staining of delta-like ligand 4, Ki67 in primary glioblastoma (×400): (A) positive staining of delta-like ligand 4 primarily distributed in the cytoplasm of tumor endothelial cells and seldom detected in some tumor cells; (B) positive nuclear staining of Ki67 in both tumor endothelial cells and tumor cells. Positive CD34 staining in primary glioblastoma (C) and adjacent nonneoplastic brain tissues (D) (×200): (C) CD34 (microvessel density) high expressed in primary glioblastoma; (D) low CD34 (microvessel density) expression was seen in adjacent nonneoplastic brain tissues (positive staining in tumor endothelial cells: red arrow; positive staining in tumor cells: green arrow)

Figure 2: Immunohistochemical staining for delta-like ligand 4, Ki67, and CD34 expression. (A and B) Positive staining of delta-like ligand 4, Ki67 in primary glioblastoma (×400): (A) positive staining of delta-like ligand 4 primarily distributed in the cytoplasm of tumor endothelial cells and seldom detected in some tumor cells; (B) positive nuclear staining of Ki67 in both tumor endothelial cells and tumor cells. Positive CD34 staining in primary glioblastoma (C) and adjacent nonneoplastic brain tissues (D) (×200): (C) CD34 (microvessel density) high expressed in primary glioblastoma; (D) low CD34 (microvessel density) expression was seen in adjacent nonneoplastic brain tissues (positive staining in tumor endothelial cells: red arrow; positive staining in tumor cells: green arrow)